When Christians banned other religions and philosophies in the late 4th century, Plato and Aristotle, pagans who believed in the immortality of the soul, could ultimately be accommodated by Christianity; but Epicureanism could not. The Epicureans believed life was about seeking pleasure and, if there was pain, it would end with death. Christians, on the other hand, thought life should be difficult, pleasure was evil, and pain could last for eternity. Therefore they had to wipe out all memory of the Epicureans and change the meaning of the term into someone who is a glutton.
Here’s a short clip from the show: